Research Projects
New applications of solid-state NMR to the extracellular matrix
SsNMR is a versatile technique that can provide atomic-level structural information on complex materials in functionally-relevant states, with unique advantages for investigating the extracellular matrix.
Pigmentation in alkaptonuria
Alkaptonuria is a rare disease that can lead to servere pigmentation of various body tissues, which is associated with tissue degradation. While visually striking, the chemical nature of the pigment is still not well-understood. By characterizing in vitro-generated pigment using a variety of chemical techniques, we aim to understand the nature of the pigmentation species and illuminate new clinical approaches to prevent or reverse its formation.